The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Jan. 11, 2017
Applicant:
The Rockefeller University, New York, NY (US);
Inventors:
Sohail Tavazoie, New York, NY (US);
Masoud Tavazoie, New York, NY (US);
Assignee:
The Rockefeller University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/195 (2006.01); A61K 38/14 (2006.01); A61P 31/12 (2006.01); A61P 31/04 (2006.01); A61P 35/00 (2006.01); A61K 31/4174 (2006.01); A61K 31/675 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/195 (2013.01); A61K 31/4174 (2013.01); A61K 31/675 (2013.01); A61K 38/14 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); A61P 31/12 (2018.01); A61P 35/00 (2018.01);
Abstract
The invention features methods of treating disorders related to increased levels of myeloid derived suppressor cells such as cancer or infections. The disclosure also provides methods of treating cancer including combinations of LXRβ agonists and immunotherapies such as PD1 inhibitors, PDL1 inhibitors, and adoptive T-cell transfer therapy.