The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2023

Filed:

Aug. 02, 2018
Applicant:

Intelgenx Corp., St-Laurent, CA;

Inventors:

Mobarik Bilal, Montreal, CA;

Rodolphe Obeid, Pierrefonds, CA;

Nadine Paiement, St-Laurent, CA;

Assignee:

Intelgenx Corp., St-Laurent, CA;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/553 (2006.01); A61K 47/10 (2017.01); A61K 47/28 (2006.01); A61K 9/70 (2006.01); A61K 9/00 (2006.01); A61K 47/36 (2006.01); A61K 47/32 (2006.01); A61K 47/26 (2006.01); A61K 47/18 (2017.01); A61K 47/38 (2006.01);
U.S. Cl.
CPC ...
A61K 9/7015 (2013.01); A61K 9/006 (2013.01); A61K 9/7007 (2013.01); A61K 31/553 (2013.01); A61K 47/10 (2013.01); A61K 47/186 (2013.01); A61K 47/26 (2013.01); A61K 47/28 (2013.01); A61K 47/32 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01);
Abstract

A loxapine film oral dosage form includes loxapine salt, free base, or prodrug in an amount effective to provide relief from acute agitation associated with schizophrenia or bipolar 1 disorder via oral transmucosal delivery, dispersed in a polymeric film forming system. Advantageously, the film oral dosage form further includes a sweetener, a refreshing agent, an antioxidant, a pH stabilizer, a penetration enhancer, a mucoadhesive agent and a plasticizer. The loxapine film oral dosage form provides rapid onset of relief from acute agitation associated with schizophrenia or bipolar 1 disorder without presenting pulmonary health risks, thereby reducing risks to patients and others.


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