The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Jan. 12, 2018
Applicant:
Duke University, Durham, NC (US);
Inventors:
Ashutosh Chilkoti, Durham, NC (US);
Davoud Mozhdehi, Durham, NC (US);
Kelli M. Luginbuhl, Durham, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/42 (2017.01); C07K 14/78 (2006.01); A61K 38/00 (2006.01); A61K 9/107 (2006.01); C12N 1/20 (2006.01); C12N 9/10 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1075 (2013.01); A61K 47/42 (2013.01); C07K 14/78 (2013.01); C12N 1/20 (2013.01); C12N 9/1029 (2013.01); C12P 21/00 (2013.01); C12Y 203/01097 (2013.01); A61K 38/00 (2013.01); C07K 2319/033 (2013.01); C07K 2319/735 (2013.01); C07K 2319/90 (2013.01); C12N 2501/00 (2013.01);
Abstract
Disclosed herein are conjugates including a fatty acid, a self-assembly domain, and a polypeptide, where the conjugates have phase transition behavior. Further disclosed are methods of using the conjugates to treat disease, methods of delivering an agent, and methods of preparing the conjugates.