The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2023

Filed:

Dec. 13, 2019
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

British Columbia Cancer Agency Branch, Vancouver, CA;

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Julius-maximilians-university of Würzburg, Würzburg, DE;

Board of Regents of the University of Nebraska, Lincoln, NE (US);

Oslo University Hospital Hf, Oslo, NO;

Hospital Clinic DE Barcelona, Barcelona, ES;

Universitat DE Barcelona, Barcelona, ES;

Institut D'investigacions Biomèdiques August Pi I Sunyer (Idibaps), Barcelona, ES;

Robert Bosch Gesellschaft Fuer Medizinische Forschung Mbh, Stuttgart, DE;

Oregon Health & Science University, Portland, OR (US);

City of Hope, Duarte, CA (US);

The Cleveland Clinic Foundation, Cleveland, OH (US);

Inventors:

Louis M. Staudt, Bethesda, MD (US);

Christian Steidl, North Vancouver, CA;

Anja Mottok, Ulm, DE;

George W. Wright, Rockville, MD (US);

David William Scott, Vancouver, CA;

Lisa M. Rimsza, Scottsdale, AZ (US);

Andreas Rosenwald, Würzburg, DE;

Randy Gascoyne, North Vancouver, CA;

Timothy Greiner, Council Bluffs, IA (US);

Dennis Weisenburger, Glendora, CA (US);

Erlend B. Smeland, Oslo, NO;

Jan Delabie, Toronto, CA;

Elias Campo Guerri, Barcelona, ES;

German Ott, Bitighein-Bissingen, DE;

Rita Braziel, West Linn, OR (US);

Elaine S. Jaffe, Great Falls, VA (US);

Kai Fu, Omaha, NE (US);

Wing C. Chan, Pasadena, CA (US);

Joo Song, Duarte, CA (US);

James R. Cook, Shaker Heights, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G16B 5/00 (2019.01); G16B 25/10 (2019.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
G16B 5/00 (2019.02); C12Q 1/6886 (2013.01); G16B 25/10 (2019.02); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01);
Abstract

In embodiments of the invention, the invention provides a method for distinguishing between lymphoma types based on gene expression measurements. In embodiments, the invention distinguishes between PMBCL and DLBCL based on gene expression signatures, and can further distinguish between DLBCL subtypes. In embodiments of the invention, the distinctions are used in methods of treatment.


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