The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2023

Filed:

Jul. 14, 2021
Applicant:

Æterna Zentaris Gmbh, Charleston, SC (US);

Inventors:

Nicola Ammer, Frankfurt, DE;

Michael Teifel, Weiterstadt, DE;

Beate Aue, Aschaffenburg, DE;

Assignee:

ÆTERNA ZENTARIS GMBH, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/74 (2006.01); A61K 38/27 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
G01N 33/74 (2013.01); A61K 38/27 (2013.01); G01N 33/49 (2013.01); G01N 2333/61 (2013.01); G01N 2800/04 (2013.01); G01N 2800/38 (2013.01);
Abstract

The present invention provides a method for measuring growth hormone level in a human child, including a method of assessing pituitary-related growth hormone deficiency in a human child as a stand-alone test. The method includes the steps of oral administration of an effective amount of macimorelin to the child, collecting from the child two or three post-administration blood samples within a range of about 60 minutes after administration, and determining the level of growth hormone in the samples. The method can be used for diagnosing pituitary-related growth hormone deficiency in a child when the peak level of determined growth hormone in the samples is below a cut-off value.


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