The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2023

Filed:

Aug. 28, 2018
Applicant:

Cellino Biotech, Inc., Cambridge, MA (US);

Inventors:

Matthias Wagner, Cambridge, MA (US);

Marinna Madrid, Cambridge, MA (US);

Assignee:

CELLINO BIOTECH, INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/87 (2006.01); C12M 1/42 (2006.01); A61B 18/20 (2006.01); A61K 9/00 (2006.01); A61B 18/26 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01); B82Y 5/00 (2011.01); H01S 3/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/87 (2013.01); A61B 18/20 (2013.01); A61B 18/26 (2013.01); A61K 9/0009 (2013.01); A61K 9/0019 (2013.01); C12M 35/02 (2013.01); A61B 2017/00765 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/263 (2013.01); B82Y 5/00 (2013.01); H01S 3/00 (2013.01);
Abstract

An intracellular delivery system and method are provided. The intracellular delivery system comprises a laser-activated surface and cells positioned at a distance from the laser-activated surface. A laser provided a laser pulse that is used to porate membranes of the cells to deliver or extract cargo from the cells into a liquid surrounding the cells. The method of intracellular delivery comprises positioning a laser-activated surface at a distance from cells and applying a laser pulse from the laser to the surface to porate membranes of the cells to deliver or extract cargo from the cells into a liquid surrounding the cells.


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