The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2023
Filed:
May. 24, 2018
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Robert J. A. Bell, Oakland, CA (US);
Joseph F. Costello, Oakland, CA (US);
Daniel Lim, Oakland, CA (US);
Andrew Mancini, Oakland, CA (US);
Assignees:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);
THE UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 47/68 (2017.01); A61K 9/51 (2006.01); A61K 31/7088 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/51 (2013.01); A61K 31/7088 (2013.01); A61K 45/06 (2013.01); A61K 47/6807 (2017.08); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3513 (2013.01);
Abstract
The present invention provides methods for cancers associated with a TERT promoter mutation in a subject. In some embodiments, the methods comprise administering to the subject a therapeutically effective amount of an agent that specifically reduces or inhibits GA binding protein transcription factor beta subunit 1 long isoform (GABPBIL) expression or function.