The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2023
Filed:
Jul. 26, 2022
Glyconex Inc., New Taipei, TW;
Tong-Hsuan Chang, New Taipei, TW;
Mei-Chun Yang, New Taipei, TW;
Liahng-Yirn Liu, New Taipei, TW;
Jerry Ting, New Taipei, TW;
Shu-Yen Chang, New Taipei, TW;
Yen-Ying Chen, New Taipei, TW;
Yu-Yu Lin, New Taipei, TW;
Shu-Lun Tang, New Taipei, TW;
GlycoNex Inc., New Taipei, TW;
Abstract
Disclosed herein are humanized antibodies, antigen-binding fragments thereof, and antibody conjugates, that are capable of specifically binding to certain biantennary Lewis antigens, which antigens are expressed in a variety of cancers. The presently disclosed antibodies are useful to target antigen-expressing cells for treatment or detection of disease, including various cancers. Also provided are polynucleotides, vectors, and host cells for producing the disclosed antibodies and antigen-binding fragments thereof. Pharmaceutical compositions, methods of treatment and detection, and uses of the antibodies, antigen-binding fragments, antibody conjugates, and compositions are also provided.