The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2023
Filed:
Jul. 19, 2019
The Board of Regents of the University of Oklahoma, Norman, OK (US);
Robert H. Cichewicz, Norman, OK (US);
Lin Du, Norman, OK (US);
Jianlan You, Norman, OK (US);
Allison O. Mattes, Avondale, AZ (US);
Shikha Srivastava, Norman, OK (US);
Saikat Haldar, Debipur, IN;
The Board of Regents of the University of Oklahoma, Norman, OK (US);
Abstract
Cyclic depsipeptide-class molecules, referred to herein as persephacins (including analogs thereof), having similarities to aureobasidin A, are described. The persephacins have antimicrobial activity, such as antifungal activity against a diverse range of clinically-relevant fungal pathogens, antiprotozoan parasite activity, and antibacterial activity, and can be used for example in treatments of difficult-to-treat ocular fungal infections at lower concentrations than natamycin. The active compounds may be combined with a secondary compound in a composition.