The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2023

Filed:

Feb. 11, 2021
Applicant:

Chang Gung Memorial Hospital, Taoyuan, TW;

Inventors:

John Yu, La Jolla, CA (US);

Alice Yu, La Jolla, CA (US);

Sheng-Hung Wang, Taipei, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); A61K 38/08 (2019.01); A61K 47/69 (2017.01); A61K 47/60 (2017.01); C07K 16/32 (2006.01); A61K 51/08 (2006.01); C07K 7/08 (2006.01); A61K 38/10 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 31/353 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 31/353 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 39/39558 (2013.01); A61K 47/60 (2017.08); A61K 47/6907 (2017.08); A61K 51/08 (2013.01); A61P 35/00 (2018.01); C07K 7/08 (2013.01); C07K 16/32 (2013.01); C07K 2317/31 (2013.01);
Abstract

An isolated cancer-targeting peptide that includes at least two copies of the amino acid sequence PFLP (SEQ ID NO: 1) or PFLF (SEQ ID NO: 2). Also disclosed is a pharmaceutical composition for treating cancer. The composition contains the isolated cancer-targeting peptide and an anti-cancer agent. Further disclosed is a bispecific anti-cancer antibody that includes the isolated cancer-targeting peptide and an antigen-binding peptide that stimulates T cell activity. Methods are provided for treating cancer by administering the pharmaceutical composition or the bispecific anti-cancer antibody. Further provided is a method for diagnosing cancer by administering a radionuclide-labeled cancer-targeting peptide to an individual and imaging a location of the radionuclide.


Find Patent Forward Citations

Loading…