The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2023

Filed:

Jul. 23, 2021
Applicant:

Glaxosmithkline Llc, New Castle, DE (US);

Inventors:

Kevin J. Duffy, Collegeville, PA (US);

Duke M. Fitch, Collegeville, PA (US);

Jian Jin, Collegeville, PA (US);

Ronggang Liu, Collegeville, PA (US);

Antony N. Shaw, Collegeville, PA (US);

Kenneth Wiggall, Collegeville, PA (US);

Assignee:

GlaxoSmithKline LLC, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/54 (2006.01); C07D 239/60 (2006.01); A61K 31/515 (2006.01); C07D 239/62 (2006.01); C07D 401/04 (2006.01); C07D 405/04 (2006.01); C07D 405/10 (2006.01); C07D 409/04 (2006.01); C07D 409/10 (2006.01); C07D 413/06 (2006.01); C07D 413/10 (2006.01); C07D 417/10 (2006.01); C07D 239/22 (2006.01);
U.S. Cl.
CPC ...
C07D 239/60 (2013.01); A61K 31/515 (2013.01); C07D 239/22 (2013.01); C07D 239/54 (2013.01); C07D 239/62 (2013.01); C07D 401/04 (2013.01); C07D 405/04 (2013.01); C07D 405/10 (2013.01); C07D 409/04 (2013.01); C07D 409/10 (2013.01); C07D 413/06 (2013.01); C07D 413/10 (2013.01); C07D 417/10 (2013.01);
Abstract

The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.


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