The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2023
Filed:
Jul. 28, 2020
Applicant:
Transcriptx, Inc., Sunnyvale, CA (US);
Inventors:
David J. Lockhart, Emerald Hills, CA (US);
Brandon Wustman, San Diego, CA (US);
Mirko Hennig, Sunnyvale, CA (US);
Daniella Ishimaru, Sunnyvale, CA (US);
Assignee:
TranscripTx, Inc., Sunnyvale, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 9/127 (2006.01); A61K 31/7105 (2006.01); A61K 31/7115 (2006.01); A61P 11/06 (2006.01); C12N 15/113 (2010.01); A61K 47/69 (2017.01); A61P 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/005 (2013.01); A61K 9/1271 (2013.01); A61K 31/7105 (2013.01); A61K 31/7115 (2013.01); A61K 47/6925 (2017.08); A61K 48/0041 (2013.01); A61P 11/00 (2018.01); A61P 11/06 (2018.01); C12N 15/113 (2013.01);
Abstract
Polynucleotides encoding peptides, proteins, enzymes, and functional fragments thereof are disclosed. The polynucleotides of the disclosure can be effectively delivered to an organ, such as the lung, and expressed within cells of the organ. The polyribonucleotides of the disclosure can be used to treat a disease or condition associated with cilia maintenance and function, impaired function of the axoneme, such as DNAI1 or DNAH5.