The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2023
Filed:
May. 22, 2019
Applicant:
Mogam Institute for Biomedical Research, Yongin-si, KR;
Inventors:
Assignee:
MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH, Yongin-si, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/25 (2006.01); A61P 31/22 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/25 (2013.01); A61P 31/22 (2018.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); C12N 2710/16722 (2013.01); C12N 2710/16734 (2013.01); C12N 2710/16771 (2013.01);
Abstract
An antigen variant and a use thereof are disclosed. The antigen variant is a protein, among surface proteins (gE) of the varicella zoster virus, exhibits a high expression level and high immunogenicity, and thus, when the antigen variant is used as a vaccine composition, the vaccine composition has more excellent safety compared to a live virus vaccine, and the antigen variant exhibits a higher expression level in a host cell compared to other antigens. The antigen variant is useful as a vaccine for preventing or treating chicken pox or herpes zoster caused by the varicella zoster virus.