logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11642362 B1

PDFFull Text
Date of Patent:
May. 09, 2023

Filed:

Jul. 06, 2018

Methods of inhibiting cell proliferation and mettl8 activity

Applicant:

National University of Singapore, Singapore, SG;

Inventors:

Xin-Yuan Fu, Singapore, SG;

Xinyu Liu, Singapore, SG;

Lu Ang Xu, Singapore, SG;

Assignee:

NATIONAL UNIVERSITY OF SINGAPORE, Singapore, SG;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Jane J Zara

Int. Cl.
CPC ...
A61K 31/7105 (2006.01); A61P 35/00 (2006.01); A61K 31/122 (2006.01); A61K 31/13 (2006.01); A61K 31/18 (2006.01); A61K 31/192 (2006.01); A61K 31/282 (2006.01); A61K 31/37 (2006.01); A61K 31/407 (2006.01); C12N 15/113 (2010.01); C12N 15/86 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7105 (2013.01); A61K 31/122 (2013.01); A61K 31/13 (2013.01); A61K 31/18 (2013.01); A61K 31/192 (2013.01); A61K 31/282 (2013.01); A61K 31/37 (2013.01); A61K 31/407 (2013.01); A61P 35/00 (2018.01); C12N 15/1137 (2013.01); C12N 15/86 (2013.01); A61K 45/06 (2013.01);
Abstract

The disclosure provides a method of inhibiting proliferation of a cell, inhibiting m3C formation in a cell, inhibiting activity of Mettl8 in a cell, or activating ATM and p53 in a cell, the method comprising contacting the cell with a Mettl8 inhibitor. The disclosure also provides a composition comprising a cell with a reduced expression or activity of Mettl8. In another aspect, the disclosure provides methods of rendering a tumor cell sensitive to a cancer therapy.

Find Patent Forward Citations

Fu, Xin-Yuan. (2023). Methods of inhibiting cell proliferation and mettl8 activity (U.S. Patent No. 11642362). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11642362

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…