The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2023

Filed:

Jan. 08, 2021
Applicant:

Woolsey Pharmaceuticals, Inc., New York, NY (US);

Inventors:

Thomas MacAllister, Arlington, VA (US);

Sven Jacobson, New York, NY (US);

Assignee:

Woolsey Pharmaceuticals, Inc., St. Petersburg, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/551 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/551 (2013.01); A61P 25/28 (2018.01);
Abstract

The invention is based on the discovery that rho kinase inhibitors can be used to treat proteinopathy associated wandering. A number of degenerative neurological diseases are thought to be caused, at least in part, by the formation of protein aggregates that cause neurotoxicity and progressive decline in function. The inventive methods related to the use of rho kinase inhibitors in the treatment of patients with proteinopathy-associated wandering. The patients may be suffering from Huntington's disease, a traumatic brain injury, autism spectrum disorder, Down syndrome or a proteinopathy-associated dementia, such as Alzheimer disease or frontotemporal dementia.


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