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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11642332 B1

PDFFull Text
Date of Patent:
May. 09, 2023

Filed:

May. 14, 2021

(2r,4r)-5-(5'-chloro-2′-fluorobiphenyl-4-yl)-2-hydroxy-4-[(5-methyloxazole-2-carbonyl)amino]pentanoic acid

Applicant:

Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);

Inventors:

Melissa Fleury, Brisbane, CA (US);

Adam D. Hughes, Half Moon Bay, CA (US);

Anne-Marie Beausoleil, Redwood City, CA (US);

Erik Fenster, San Bruno, CA (US);

Venkat R. Thalladi, Foster City, CA (US);

Miroslav Rapta, San Carlos, CA (US);

Assignee:

THERAVANCE BIOPHARMA R&D IP, LLC, South San Francisco, CA (US);

Attorney:

Sheppard Mullin Richter & Hampton LLP

Primary Examiner:

Michael Barker

Int. Cl.
CPC ...
A61K 31/421 (2006.01); A61K 9/48 (2006.01); A61K 47/12 (2006.01); C07D 263/34 (2006.01); C30B 7/14 (2006.01); C30B 29/54 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/421 (2013.01); A61K 9/4816 (2013.01); A61K 9/4825 (2013.01); A61K 45/06 (2013.01); A61K 47/12 (2013.01); C07D 263/34 (2013.01); C30B 7/14 (2013.01); C30B 29/54 (2013.01); C07B 2200/13 (2013.01);
Abstract

In one aspect, the invention relates to a compound of the structure: or a pharmaceutically acceptable salt thereof, and a crystalline form of this compound, having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising this compound; methods of using this compound; and processes for preparing this compound.

Find Patent Forward Citations

Fleury, Melissa. (2023). (2r,4r)-5-(5'-chloro-2′-fluorobiphenyl-4-yl)-2-hydroxy-4-[(5-methyloxazole-2-carbonyl)amino]pentanoic acid (U.S. Patent No. 11642332). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11642332

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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