The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2023

Filed:

Nov. 04, 2022
Applicant:

Isla Technologies, Inc., San Carlos, CA (US);

Inventors:

Sara Joan Photiadis, San Francisco, CA (US);

Douglas Marc Photiadis, Alexandria, VA (US);

Thomas A. Kramer, San Carlos, CA (US);

Assignee:

ISLA Technologies, Inc., San Carlos, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61F 2/02 (2006.01); A61F 2/07 (2013.01); A61K 35/39 (2015.01); C12N 5/071 (2010.01); A61F 2/90 (2013.01); A61L 27/56 (2006.01); A61L 31/00 (2006.01); A61L 31/08 (2006.01);
U.S. Cl.
CPC ...
A61F 2/022 (2013.01); A61F 2/07 (2013.01); A61F 2/90 (2013.01); A61K 35/39 (2013.01); A61L 27/56 (2013.01); A61L 31/005 (2013.01); A61L 31/08 (2013.01); C12N 5/0678 (2013.01); A61F 2210/0004 (2013.01); A61F 2210/0076 (2013.01); A61F 2220/0075 (2013.01); A61F 2240/002 (2013.01); A61F 2250/0067 (2013.01); A61L 2300/608 (2013.01); A61L 2300/64 (2013.01); A61L 2420/08 (2013.01); C12N 2513/00 (2013.01);
Abstract

A bioartificial device, such as a bioartificial pancreas, for implantation in a patient's vascular system. The bioartificial pancreas includes a scaffold adapted to engage an interior wall of a blood vessel, a cellular complex support by the scaffold and extending longitudinally within the interior cavity of the scaffold so as to be exposed to the blood flow when the scaffold is engaged with the blood vessel, the cellular complex support comprising one or more pockets bordered by thin film; and cellular complex comprising pancreatic islets disposed in the one or more pockets, the thin film being adapted to permit oxygen and glucose to diffuse from flowing blood into the one or more pockets at a rate sufficient to support the viability of the islets. The invention also includes methods of making and using a bioartificial pancreas.


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