The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2023

Filed:

Jul. 18, 2018
Applicant:

Headwall Photonics, Inc., Bolton, MA (US);

Inventors:

David Bannon, Hopkinton, MA (US);

Domhnull Granquist-Fraser, Acton, MA (US);

Paul Bartel, Woburn, MA (US);

Kevin Didona, Chelmsford, MA (US);

Carson Roberts, Roslindale, MA (US);

Blair Simon, Clinton, MA (US);

Assignee:

Headwall Photonics, Inc., Bolton, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/1455 (2006.01);
U.S. Cl.
CPC ...
A61B 5/4064 (2013.01); A61B 5/0075 (2013.01); A61B 5/0082 (2013.01); A61B 5/14552 (2013.01); A61B 5/14553 (2013.01); A61B 5/4088 (2013.01); A61B 5/6814 (2013.01); A61B 5/7246 (2013.01); A61B 5/0042 (2013.01); A61B 5/0059 (2013.01); A61B 5/0062 (2013.01); A61B 5/0073 (2013.01); A61B 5/1455 (2013.01); A61B 2562/0233 (2013.01);
Abstract

A device and system for non-invasively measuring wavelength-dependent changes in optical absorption of brain tissue damaged by CTE, TBI, concussion, repetitive trauma, and/or Lou Gehrig's disease in comparison to signals from healthy normal tissue for a subject in vivo. The brain, tissues, and fluids superficial to the brain are trans-cranially illuminated by light source(s) in low-absorption spectral windows for tissue in the visible and/or near-infrared parts of the spectrum. Optode(s) are disposed at predetermined radial distance(s) from a light output to collect the scattered and/or deflected signal from the surface of the head. The predetermined radial distance from the light output to the optode is correlated with the depth of tissue penetration for the light collected by the optode. A spectrometer and computer analyze the collected light for characteristic optical signatures of the brain tissue damage utilizing the absorbance and/or reflectance and/or transmission spectra generated as a result.


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