The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2023
Filed:
Jun. 29, 2022
Applicant:
The Regents of the University of Colorado, Denver, CO (US);
Inventors:
Andrew Garst, Boulder, CO (US);
Ryan T Gill, Denver, CO (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE, Denver, CO (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/90 (2006.01); C12N 15/10 (2006.01); C40B 40/08 (2006.01); C12N 15/11 (2006.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12N 15/902 (2013.01); C12N 9/22 (2013.01); C12N 15/102 (2013.01); C12N 15/1024 (2013.01); C12N 15/1082 (2013.01); C12N 15/1093 (2013.01); C12N 15/11 (2013.01); C12N 15/111 (2013.01); C40B 40/08 (2013.01); C12N 2310/10 (2013.01); C12N 2310/20 (2017.05); C12N 2320/11 (2013.01); C12N 2320/12 (2013.01); C12N 2330/31 (2013.01);
Abstract
Described herein are molecules for editing a cell. The molecules described herein generally comprise the following covalently-linked components and a nucleic acid encoding a guide RNA (gRNA) sequence targeting a target region in a cell and a region homologous to the target region comprising a change in sequence relative to the target region.