The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2023
Filed:
Mar. 03, 2020
Applicant:
Macrogenics, Inc., Rockville, MD (US);
Inventors:
Leslie S. Johnson, Darnestown, MD (US);
Ezio Bonvini, Potomac, MD (US);
Chia-Ying Kao Lam, San Jose, CA (US);
Paul A. Moore, North Potomac, MD (US);
Liqin Liu, Germantown, MD (US);
Scott Koenig, Rockville, MD (US);
Assignee:
MacroGenics, Inc., Rockville, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/46 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 39/39558 (2013.01); C07K 16/2809 (2013.01); C07K 16/2896 (2013.01); C07K 16/3061 (2013.01); C07K 16/468 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/35 (2013.01); C07K 2317/524 (2013.01); C07K 2317/526 (2013.01); C07K 2317/56 (2013.01); C07K 2317/569 (2013.01); C07K 2317/626 (2013.01); C07K 2317/73 (2013.01); C07K 2317/90 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract
CD19×CD3 bi-specific monovalent diabodies, and particularly, CD19×CD3 bi-specific monovalent Fc diabodies, are capable of simultaneous binding to CD19 and CD3, and are used in the treatment of hematologic malignancies.