The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2023
Filed:
Jan. 29, 2019
Applicant:
Stichting Radboud Universiteit, Nijmegen, NL;
Inventors:
Thomas Jan Boltje, Doorn, NL;
Torben Heise, Lyons, FR;
Johan Franciscus Adrianus Pijnenborg, Nijmegen, NL;
Christian Büll, Copenhagen, DK;
Gosse Jan Adema, Groesbeek, NL;
Assignees:
STICHTING RADBOUD UNIVERSITEIT, Nijmegen, NL;
STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM, Nijmegen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 13/12 (2006.01); C07H 13/04 (2006.01);
U.S. Cl.
CPC ...
C07H 13/12 (2013.01); C07H 13/04 (2013.01);
Abstract
The present invention relates to a new class of sialyltransferase inhibitors. The class features a carbamate or similar moiety on the amine of a neuraminic acid derivative. Such inhibitors are suitable for use as a medicament, for example for treating, preventing, or delaying bacterial infection, viral infection, cancer, a disorder of sialic acid metabolism, or an autoimmune disease.