The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2023

Filed:

Mar. 12, 2019
Applicants:

Luoxin Pharmaceutical (Shanghai) Co., Ltd., Shanghai, CN;

Shandong Luoxin Pharmaceutical Group Stock Co., Ltd., Shandong, CN;

Medshine Discovery Inc., Jiangsu, CN;

Inventors:

Kevin X Chen, Shanghai, CN;

Xiaobing Yan, Shanghai, CN;

Jianglei Huang, Shanghai, CN;

Yuekun Nie, Shanghai, CN;

Guoping Hu, Shanghai, CN;

Jian Li, Shanghai, CN;

Shuhui Chen, Shanghai, CN;

Jiaqiang Dong, Shanghai, CN;

Tie-Lin Wang, Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/22 (2006.01); C07D 487/04 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 35/00 (2018.01); C07D 519/00 (2013.01);
Abstract

Disclosed is a novel class of MDM2-p53 inhibitor compounds having an imidaxopyrolone structure, and specifically disclosed are compounds represented by formulas (I-1) and (I-2) and pharmaceutically acceptable salts thereof.


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