The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2023
Filed:
May. 04, 2018
Applicant:
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Inventors:
Stephen F. Badylak, West Lafayette, IN (US);
Anne E. Faust, Pittsburgh, PA (US);
George S. Hussey, Cranberry Township, PA (US);
Yolandi Van der Merwe, Pittsburgh, PA (US);
Michael Brandt Steketee, Pittsburgh, PA (US);
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/22 (2015.01); A61K 9/00 (2006.01); A61K 38/44 (2006.01); A61K 45/06 (2006.01); A61K 9/51 (2006.01); C12N 15/113 (2010.01); A61P 27/02 (2006.01); A61P 27/06 (2006.01); A61K 9/06 (2006.01);
U.S. Cl.
CPC ...
A61K 35/22 (2013.01); A61K 9/0048 (2013.01); A61K 9/06 (2013.01); A61K 9/5176 (2013.01); A61K 38/44 (2013.01); A61K 45/06 (2013.01); A61P 27/02 (2018.01); A61P 27/06 (2018.01); C12N 15/1135 (2013.01); C12Y 104/03013 (2013.01); C12N 2310/141 (2013.01);
Abstract
Methods are disclosed herein for increasing retinal ganglion cell survival in a subject in need thereof. These methods include selecting a subject in need of increased retinal ganglion cell survival and administering a therapeutically effective amount of isolated nanovesicles derived from an extracellular matrix (MBVs) to the subject.