The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2023
Filed:
Mar. 28, 2018
Applicant:
Shionogi & Co., Ltd., Osaka, JP;
Inventors:
Akira Kugimiya, Toyonaka, JP;
Mitsuaki Sekiguchi, Amagasaki, JP;
Norikazu Kuroda, Toyonaka, JP;
Jun Nakamura, Toyonaka, JP;
Tetsuya Tanino, Toyonaka, JP;
Yasunori Mitsuoka, Toyonaka, JP;
Takeshi Kasuya, Osaka, JP;
Yasuharu Kato, Toyonaka, JP;
Assignee:
SHIONOGI & CO., LTD., Osaka, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7088 (2006.01); A61K 47/50 (2017.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); A61K 47/50 (2017.08); C12N 15/113 (2013.01);
Abstract
The purpose of the present invention is to provide novel complexes that improve the effect of nucleic acid medicines. Provided is a complex in which a multibranched lipid(s) binds through a linker to a strand of an oligonucleotide comprising a nucleic acid medicine having suppressing activity of the target gene expression.