The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2023

Filed:

Jul. 15, 2020
Applicant:

Molecure S.a., Warsaw, PL;

Inventors:

Marzena Mazur, Lodz, PL;

Gleb Andryianau, Warsaw, PL;

Lukasz Joachimiak, Lodz, PL;

Wojciech Czestkowski, Pabianice, PL;

Michal Kowalski, Godziszka, PL;

Piotr Niedziejko, Warsaw, PL;

Sylwia Olejniczak, Lodz, PL;

Krzysztof Matyszewski, Lodz, PL;

Robert Koralewski, Lodz, PL;

Jacek Olczak, Lodz, PL;

Adam Golebiowski, Madison, CT (US);

Agnieszka Bartoszewicz, Warsaw, PL;

Assignee:

Molecure S.A., Warsaw, PL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 413/14 (2006.01); A61K 31/00 (2006.01); A61K 31/5365 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/5355 (2006.01); A61K 45/06 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5365 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/5355 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 413/14 (2013.01); C07D 498/04 (2013.01);
Abstract

Disclosed are amino triazole compounds of formula (I). These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.


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