The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2023

Filed:

May. 18, 2018
Applicant:

Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);

Inventor:

Nongjian Tao, Fountain Hills, AZ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/557 (2006.01); G01N 33/84 (2006.01); G01N 33/552 (2006.01); G01N 33/553 (2006.01); G01N 33/543 (2006.01); G01B 11/14 (2006.01); G01N 21/17 (2006.01); C12Q 1/6825 (2018.01);
U.S. Cl.
CPC ...
G01N 33/557 (2013.01); C12Q 1/6825 (2013.01); G01N 33/543 (2013.01); G01N 33/552 (2013.01); G01N 33/553 (2013.01); G01N 33/84 (2013.01); G01B 11/14 (2013.01); G01N 2021/1721 (2013.01);
Abstract

An apparatus for label-free analysis of molecules, including interactions and reactions of the molecules, is disclosed. The apparatus is based on detecting molecule movement under the influence of an external electric field. The apparatus is able to achieve sensitive detection of molecular binding to proteins or other molecules, and conformational changes of proteins or other molecules and biochemical reactions of the proteins or other molecules. Applications of the apparatus include screening of drug molecules, kinetic analysis of posttranslational modification of proteins, and small molecule-protein interactions.


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