The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2023

Filed:

Jul. 22, 2021
Applicant:

Simpore Inc., West Henrietta, NY (US);

Inventors:

Jared A. Carter, Rochester, NY (US);

Akash S. Patel, Burlington, VT (US);

Cassandra R. Walinski, Scottsville, NY (US);

James A. Roussie, Rochester, NY (US);

Assignee:

Simpore Inc., West Henrietta, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 61/02 (2006.01); B01D 61/14 (2006.01); B01D 65/08 (2006.01); G01N 1/28 (2006.01); G01N 1/40 (2006.01); B01D 71/02 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
G01N 1/4005 (2013.01); B01D 61/027 (2013.01); B01D 61/147 (2013.01); B01D 65/08 (2013.01); B01D 71/02 (2013.01); B01D 71/022 (2013.01); B01L 3/502753 (2013.01); G01N 1/28 (2013.01); B01D 2317/025 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0896 (2013.01); G01N 2001/4016 (2013.01);
Abstract

Provided are methods, devices, and kits for the isolation of extracellular vesicles using silicon nanomembranes. A method for EV isolation includes the steps of collecting a biofluid sample, contacting the biofluid sample with a pre-filtration membrane, thereby forming a first filtrate and a first retentate, optionally, washing the first retentate of the pre-filtration membrane, contacting the first filtrate from the pre-filtration membrane with a capture membrane, thereby forming a second filtrate and a second retentate, optionally, washing the second retentate, and eluting the second retentate from the capture membrane or lysing the second retentate to recover the contents.


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