The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2023

Filed:

Jun. 23, 2015
Applicant:

Global Life Sciences Solutions Operations Uk Ltd, Sheffield, GB;

Inventors:

Alison Myfanwy Wakefield, Cardiff, GB;

Jeffrey Kenneth Horton, Cardiff, GB;

Peter James Tatnell, Cardiff, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/00 (2006.01); G01N 1/28 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6841 (2018.01); G01N 33/574 (2006.01); B01L 3/00 (2006.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
G01N 1/2813 (2013.01); B01L 3/508 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6841 (2013.01); G01N 33/574 (2013.01); B01L 2200/16 (2013.01); G01N 2001/282 (2013.01);
Abstract

Disclosed is a method for capturing the spatial molecular profiling of a biological mass formed from biological material, comprising the steps of: a) providing a transected biological mass, for example a tumour, the transection exposing at least a portion of the mass; b) providing a solid support of an area at least equalling the area of said portion of the mass; c) transferring biological material from the portion of the mass to the support to provide on the support a two dimensional imprint of the biological material present at the portion of the mass; and d) performing a biological assay of the transferred biological material from different predetermined locations of the imprint in order to determine the spatial molecular profile of the portion of the mass.


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