The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2023

Filed:

Sep. 19, 2018
Applicant:

MD Aptus Inc., Seoul, KR;

Inventors:

Yoon-Keun Kim, Gyeonggi-do, KR;

Changill Ban, Gyeongsangbuk-do, KR;

Chulhun Chang, Busan, KR;

Assignee:

MD APTUS INC., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12N 15/115 (2010.01); G01N 33/53 (2006.01); G01N 33/553 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); G01N 33/5308 (2013.01); G01N 33/553 (2013.01); G01N 33/5695 (2013.01); C12N 2310/16 (2013.01);
Abstract

The present invention relates to a DNA aptamer binding specifically to tuberculosis specific antigen 7.7 kDa (TB7.7), a biosensor for diagnosis of tuberculosis, comprising the same, and a method for providing information for diagnosis of tuberculosis. The present inventors found that not only does a DNA aptamer according to the present invention have specific binding potential to TB7.7 protein, but also the binding affinity is excellent. When used, the DNA aptamer of the present invention can be thus expected to exhibit greater stability than a conventional ELISA method using an antibody. Hence, the aptamer is expected to find useful applications in the development of compositions for tuberculosis diagnosis, biosensors for tuberculosis diagnosis, and information providing methods for tuberculosis diagnosis.


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