The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2023
Filed:
Jan. 29, 2019
Applicant:
Ipsen Biopharm Limited, Wrexham, GB;
Inventors:
Thomas Binz, Wrexham, GB;
Stefan Sikorra, Wrexham, GB;
Assignee:
IPSEN BIOPHARM LIMITED, Wrexham, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); C07K 14/33 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/33 (2013.01); A61K 38/4893 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention provides a modified botulinum neurotoxin A (BoNT/A) L-chain protease that demonstrates enhanced cleaveage of human SNAP-23 (hSNAP-23) relative to unmodified (wild-type) BoNT/A L-chain protease, together with the use thereof for cleaving hSNAP-23.