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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11634447 B1

PDFFull Text
Date of Patent:
Apr. 25, 2023

Filed:

Dec. 14, 2020

Mannose derivatives for treating bacterial infections

Applicant:

Vertex Pharmaceuticals Incorporated, Boston, MA (US);

Inventors:

Yeeman K. Ramtohul, Pierrefonds, CA;

Sanjoy Kumar Das, Pierrefonds, CA;

Caroline Cadilhac, Montreal, CA;

Thumkunta Jagadeeswar Reddy, Pierrefonds, CA;

Louis Vaillancourt, Laval, CA;

Michel Gallant, Pierrefonds, CA;

Bingcan Liu, Montreal, CA;

Evelyne Dietrich, Laval, CA;

Frederic Vallee, Montreal, CA;

Julien Martel, Montreal, CA;

Carl Poisson, Montreal, CA;

Assignee:

Vertex Pharmaceuticals Incorporated, Boston, MA (US);

Attorney:

Banner & Witcoff, Ltd.

Primary Examiner:

Layla D Berry

Int. Cl.
CPC ...
A61K 31/706 (2006.01); A61K 31/7064 (2006.01); C07H 7/02 (2006.01); C07D 413/14 (2006.01); C07D 407/14 (2006.01); C07D 495/04 (2006.01); C07D 405/14 (2006.01); C07D 309/10 (2006.01); C07H 15/26 (2006.01); C07D 409/14 (2006.01); C07H 19/056 (2006.01); C07D 417/14 (2006.01); A61P 31/04 (2006.01); C07H 7/04 (2006.01); C07H 7/06 (2006.01); C07H 19/02 (2006.01); A61K 31/7028 (2006.01); A61K 31/7034 (2006.01); A61K 31/7036 (2006.01); A61K 31/7042 (2006.01); A61K 31/7048 (2006.01); A61K 31/7056 (2006.01);
U.S. Cl.
CPC ...
C07H 7/02 (2013.01); A61K 31/706 (2013.01); A61K 31/7028 (2013.01); A61K 31/7034 (2013.01); A61K 31/7036 (2013.01); A61K 31/7042 (2013.01); A61K 31/7048 (2013.01); A61K 31/7056 (2013.01); A61K 31/7064 (2013.01); A61P 31/04 (2018.01); C07D 309/10 (2013.01); C07D 405/14 (2013.01); C07D 407/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 495/04 (2013.01); C07H 7/04 (2013.01); C07H 7/06 (2013.01); C07H 15/26 (2013.01); C07H 19/02 (2013.01); C07H 19/056 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present invention relates to compounds useful for the treatment or prevention of bacteria infections. These compounds have formula I: The invention also provides pharmaceutically acceptable compositions containing the compounds and methods of using the compositions in the treatment of bacteria infections. Finally, the invention provides processes for making compounds of the invention.

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