The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2023
Filed:
Jan. 27, 2021
Applicant:
Zogenix International Limited, Berkshire, GB;
Inventors:
Derek J. Londesbrough, Sunderland, GB;
Marc W. Andersen, Raleigh, NC (US);
Assignee:
ZOGENIX INTERNATIONAL LIMITED, Berkshire, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07C 209/28 (2006.01); C07C 51/43 (2006.01); C07C 51/08 (2006.01); C07C 45/80 (2006.01); C07C 45/72 (2006.01); C07C 209/84 (2006.01);
U.S. Cl.
CPC ...
C07C 209/28 (2013.01); C07C 45/72 (2013.01); C07C 45/80 (2013.01); C07C 51/08 (2013.01); C07C 51/43 (2013.01); C07C 209/84 (2013.01); C07B 2200/13 (2013.01);
Abstract
Methods of preparing a fenfluramine active pharmaceutical ingredient are provided. Aspects of the method include (a) hydrolyzing a 2-(3-(trifluoromethyl)phenyl)acetonitrile composition to produce a 2-(3-(trifluoromethyl)phenyl)acetic acid composition; (b) reacting the 2-(3-(trifluoromethyl)phenyl)acetic acid composition with acetic anhydride and a catalyst to produce a 1-(3-(trifluoromethyl)phenyl)propan-2-one composition; and