The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2023

Filed:

Dec. 29, 2020
Applicant:

Bio-rad Laboratories, Inc., Hercules, CA (US);

Inventors:

Kevin D. Ness, Pleasanton, CA (US);

Donald A. Masquelier, Tracy, CA (US);

Billy W. Colston, Jr., San Ramon, CA (US);

Benjamin J. Hindson, Livermore, CA (US);

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 3/02 (2006.01); B01L 7/00 (2006.01); G01N 21/3563 (2014.01); B01F 23/41 (2022.01); B01F 33/3011 (2022.01); B01F 35/10 (2022.01); C12Q 1/686 (2018.01); G01N 21/64 (2006.01); B29C 45/00 (2006.01); G01N 21/49 (2006.01); B01F 101/23 (2022.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502784 (2013.01); B01F 23/41 (2022.01); B01F 33/3011 (2022.01); B01F 35/10 (2022.01); B01L 3/0241 (2013.01); B01L 3/502715 (2013.01); B01L 7/525 (2013.01); B29C 45/006 (2013.01); B29C 45/0053 (2013.01); C12Q 1/686 (2013.01); G01N 21/3563 (2013.01); G01N 21/49 (2013.01); G01N 21/6428 (2013.01); G01N 21/6486 (2013.01); B01F 23/4143 (2022.01); B01F 23/4145 (2022.01); B01F 2101/23 (2022.01); B01L 7/52 (2013.01); B01L 2200/0673 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/10 (2013.01); B01L 2200/12 (2013.01); B01L 2300/041 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0858 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/1822 (2013.01); B01L 2400/049 (2013.01); B01L 2400/0478 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0622 (2013.01); B29C 2045/0079 (2013.01); B29L 2031/752 (2013.01); G01N 2021/6439 (2013.01); Y02A 90/10 (2018.01);
Abstract

System for performing a flow-based assay. The system may comprise a droplet generator to produce an emulsion including droplets in a carrier fluid. The system also may comprise a thermocycler including two or more temperature-controlled zones and also including a channel connected to the droplet generator for receiving the emulsion. The channel may form a single-pass continuous fluid route traversing the temperature-controlled zones multiple times, such that droplets passing through the channel are thermally cycled. The system further may comprise a detection station downstream from the thermocycler and configured to detect a signal from the droplets after such droplets have been thermally cycled by passing through the channel.


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