The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2023

Filed:

Mar. 22, 2019
Applicant:

Talis Biomedical Corporation, Redwood City, CA (US);

Inventor:

Thomas H. Cauley, III, Redwood City, CA (US);

Assignee:

TALIS BIOMEDICAL CORPORATION, Redwood City, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 1/10 (2006.01); B01F 33/30 (2022.01); B01F 33/452 (2022.01); B01J 19/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502769 (2013.01); B01F 33/30 (2022.01); B01F 33/452 (2022.01); B01L 3/5027 (2013.01); B01L 3/502707 (2013.01); B01L 3/502746 (2013.01); G01N 1/10 (2013.01); B01J 19/0046 (2013.01); B01J 2219/00585 (2013.01); B01J 2219/00596 (2013.01); B01L 3/502715 (2013.01); B01L 3/502723 (2013.01); B01L 3/527 (2013.01); B01L 2200/028 (2013.01); B01L 2200/0621 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/14 (2013.01); B01L 2200/141 (2013.01); B01L 2200/16 (2013.01); B01L 2300/042 (2013.01); B01L 2300/047 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/12 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0487 (2013.01);
Abstract

This disclosure relates to an apparatus for simultaneously filling a plurality of sample chambers. In one aspect, the apparatus comprises a common fluid source and a plurality of independent, continuous fluidic pathways. Each independent, continuous fluidic pathway comprises a sample chamber and a pneumatic compartment. The sample chamber is connected to the common fluid source, and the pneumatic compartment is connected to the sample chamber. The sample chamber comprises, in part, an assay chamber. The assay chamber comprises a monolithic substrate and a plug having optically transmissive properties. In some embodiments, the assay chamber contains a magnetic mixing element. In some embodiments, the assay chamber is a double tapered chamber. In some embodiments, a ratio of a volume of the sample chamber to a volume of the pneumatic compartment is substantially equivalent for each fluidic pathway of the plurality of fluidic pathways.


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