The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2023

Filed:

Dec. 09, 2013
Applicants:

National University Corporation Kumamoto University, Kumamoto, JP;

University of Occupational and Environmental Health, Japan, Fukuoka, JP;

Sbi Pharmaceuticals Co., Ltd., Tokyo, JP;

Inventors:

Tetsuya Yoneda, Kumamoto, JP;

Shigeru Nishizawa, Fukuoka, JP;

Junkoh Yamamoto, Fukuoka, JP;

Tohru Tanaka, Tokyo, JP;

Hidenori Itoh, Tokyo, JP;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/10 (2006.01); C07C 229/22 (2006.01); A61B 5/055 (2006.01); G01R 33/56 (2006.01); A61K 49/18 (2006.01);
U.S. Cl.
CPC ...
A61K 49/103 (2013.01); A61B 5/055 (2013.01); A61K 49/10 (2013.01); A61K 49/1836 (2013.01); C07C 229/22 (2013.01); G01R 33/5601 (2013.01);
Abstract

[Problem] To provide a nuclear magnetic resonance diagnostic agent that has a lower toxicity to organisms and reduced side effects and yet has a site specificity toward a specific cell, tissue, organ, etc. [Solution] When ALA or an ALA derivative is administered in vivo, a metabolite thereof is accumulated in a specific cell, tissue, organ, etc. Focusing on this phenomenon, a nuclear magnetic resonance analysis was performed on a site wherein the metabolite of ALA that had been administered in vivo would be possibly accumulated. As a result, it was surprisingly found that ALA and an ALA derivative are useful as a diagnostic agent whereby the aforesaid problem can be solved.


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