The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2023
Filed:
Apr. 17, 2020
Applicant:
Agensys, Inc., Northbrook, IL (US);
Inventors:
Daniel Sousa Pereira, Los Angeles, CA (US);
Faisal Hayat Malik, Cerritos, CA (US);
Josh Snyder, Santa Monica, CA (US);
Leslie Renee Butterworth, Kirkland, WA (US);
Ssucheng Jeff Hsu, Pinole, CA (US);
Peng Yang, Los Angeles, CA (US);
Claudia Isabel Guevara, South Gate, CA (US);
Assignee:
AGENSYS, INC., Northbrook, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 47/68 (2017.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6851 (2017.08); A61K 45/06 (2013.01); A61K 47/6803 (2017.08); A61K 47/6811 (2017.08); A61K 47/6849 (2017.08);
Abstract
Antibody drug conjugates (ADC's) that bind to CD37 protein and variants thereof are described herein. CD37 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention in some embodiments provide a therapeutic composition for the treatment of cancer.