The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2023
Filed:
Mar. 13, 2018
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Ivan Alferiev, Clementon, NJ (US);
Michael Chorny, Huntingdon Valley, PA (US);
Garrett M. Brodeur, Wynnewood, PA (US);
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Abstract
A co-drug according to Formula (I) or Formula (II) is provided,R—X—NH—CO—CO—OR  (I)R—X—CO—O—CH—CO—OR  (II)wherein R is a tocol moiety, a tocol analog moiety, or a capsaicinoid moiety; X is a direct bond or a linking group; and ORis the residue of an anticancer or antirestenotic agent bearing at least one hydroxyl group by which the CO—ORester linkage is formed. Nanoparticles that include the abovementioned co-drug are also provided, as well as a method of treating a cancer patient that includes administering an effective amount of the co-drug or nanoparticles.