The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2023
Filed:
Mar. 30, 2018
Applicants:
The Broad Institute, Inc., Cambridge, MA (US);
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Steven M. Corsello, Boston, MA (US);
Todd R. Golub, Cambridge, MA (US);
Eric Stefan, Cambridge, MA (US);
Robert Hilgraf, Cambridge, MA (US);
Assignees:
THE BROAD INSTITUTE, INC., Cambridge, MA (US);
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7064 (2006.01); A61K 31/4439 (2006.01); A61K 31/498 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7064 (2013.01); A61K 31/4439 (2013.01); A61K 31/498 (2013.01);
Abstract
The present invention includes CSNK1A1 inhibitors that are useful in treating or preventing a cancer in a subject. In certain embodiments, the cancer comprises a hematological cancer, such as but not limited to acute myeloid leukemia (AML) and/or MDS (myelodysplastic syndrome, including 5q-MDS). In other embodiments, the cancer comprises colon cancer.