The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2023

Filed:

Oct. 04, 2017
Applicants:

Robert K. Ernst, Silver Spring, MD (US);

Erin M. Harberts, Phoenix, MD (US);

Alison J. Scott, Silver Spring, MD (US);

Inventors:

Robert K. Ernst, Silver Spring, MD (US);

Erin M. Harberts, Phoenix, MD (US);

Alison J. Scott, Silver Spring, MD (US);

Assignee:

UNIVERSITY OF MARYLAND, BALTIMORE, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7016 (2006.01); A61P 31/00 (2006.01); A61P 29/00 (2006.01); A61K 9/00 (2006.01); C07H 13/06 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7016 (2013.01); A61K 9/0019 (2013.01); A61P 29/00 (2018.01); A61P 31/00 (2018.01); C07H 13/06 (2013.01); G01N 33/5308 (2013.01);
Abstract

The present invention provides a method of treating sepsis in a subject, comprising administering to the subject an effective amount of a compound of the formula wherein Rand Rmay be H, OH, protonated phosphate, a phosphate salt, a sugar phosphonate, or a mono-, di- or poly-saccharide, Rmay be OH or a mono-, di- or poly-saccharide, R, R, Rand Rmay be an alkyl or alkenyl chain of up to 13 carbons (for a chain of 16 carbons), and R, R, Rand Rmay be H, OH, or an alkyl or alkenyl ester of up to 16 carbons, or a salt thereof.


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