The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2023
Filed:
Sep. 02, 2020
Applicant:
Richter Gedeon Nyrt., Budapest, HU;
Inventors:
Róbert Lovas, Budapest, HU;
Sándor Mahó, Budapest, HU;
Ildikó Bacsa, Szeged, HU;
Beatrix Mayer, Pilis, HU;
Assignee:
RICHTER GEDEON NYRT., Budapest, HU;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/566 (2006.01); A61K 31/585 (2006.01); C07J 1/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/566 (2013.01); A61K 31/585 (2013.01); C07J 1/007 (2013.01);
Abstract
The invention relates to the preparation of estetrol of formula (I), derivatives thereof protected at positions 3,15α,16α,17β of general formula (III), and 3-hydroxy derivatives thereof protected at positions 15α,16α,17β of general formula (IV), and to the intermediates of general formulae (III) and (IV) applied in the process. Another aspect of the invention is the use of estetrol of formula (I) obtained by the process of the invention for the preparation of a pharmaceutical composition.