The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2023
Filed:
Jun. 12, 2017
Applicant:
Mimetas B.v., DH Oegstgeest, NL;
Inventors:
Paul Vulto, DH Oegstgeest, NL;
Sebastiaan Johannes Trietsch, DH Oegstgeest, NL;
Arnaud Nicolas, DH Oegstgeest, NL;
Assignee:
Mimetas, B.V., DH Oegstgeest, NL;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/06 (2006.01); B01L 3/00 (2006.01); C12M 3/00 (2006.01); C12M 1/00 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12M 23/16 (2013.01); B01L 3/502715 (2013.01); C12M 21/08 (2013.01); C12M 23/38 (2013.01); C12N 5/0691 (2013.01); B01L 3/5027 (2013.01); B01L 2300/041 (2013.01); B01L 2300/0858 (2013.01); C12N 2501/999 (2013.01); C12N 2506/28 (2013.01); C12N 2531/00 (2013.01); C12N 2533/30 (2013.01);
Abstract
A method of vascularising a cell aggregate on a microfluidic device, microfluidic cell culture devices comprising perfusable vascular networks and kits and assays using the microfluidic cell culture devices are described. The microfluidic devices comprise one or more capillary pressure barriers allowing for formation of an extracellular matrix gel within a confined area of the network, in which cells can be cultured for different uses.