The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2023
Filed:
Oct. 19, 2018
Applicant:
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Benjamin D. Pope, Watertown, MA (US);
Kevin Kit Parker, Cambridge, MA (US);
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); A61K 35/28 (2015.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12M 21/08 (2013.01); A61K 35/28 (2013.01); C12M 23/20 (2013.01); C12M 25/00 (2013.01); C12N 5/0653 (2013.01); C12N 2533/30 (2013.01); C12N 2533/90 (2013.01); C12N 2535/00 (2013.01);
Abstract
The present invention provides methods and systems which accommodate 3-dimensional adipocyte expansion to produce, e.g., mature adipocytes and synthetic adipose tissue with cellular properties of mature adult organisms, including cell size and cytoarchitecture, and the use of such methods and systems for, e.g., in vitro drug screening and/or toxicity assays, disease modeling, and therapeutic applications.