The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2023
Filed:
Dec. 04, 2019
Applicant:
Remegen Co., Ltd., Shandong, CN;
Inventors:
Jing Jiang, Shandong, CN;
Jianmin Fang, Shandong, CN;
Xuejing Luan, Shandong, CN;
Xuejing Yao, Shandong, CN;
Ling Wang, Shandong, CN;
Assignee:
Remegen Co., Ltd., Shandong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/71 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention relates to a bifunctional angiogenesis inhibitor, which has VEGF inhibitory activity and FGF inhibitory activity, and can inhibit VEGF and FGF dual factors-induced or high glucose-induced cell proliferation, cell migration, and/or lumen formation. The present invention also relates to the use of the bifunctional angiogenesis inhibitor in inhibiting retinal angiogenesis, such as diabetic retinopathy, age-related macular degeneration and the like.