The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2023
Filed:
Sep. 22, 2020
Applicant:
Dizal (Jiangsu) Pharmaceutical Co., Ltd., Shanghai, CN;
Inventors:
Qingbei Zeng, Shanghai, CN;
Changhe Qi, Shanghai, CN;
Honchung Tsui, Shanghai, CN;
Zhenfan Yang, Shanghai, CN;
Xiaolin Zhang, Shanghai, CN;
Assignee:
Dizal (Jiangsu) Pharmaceutical Co., Ltd., Shanghai, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 519/00 (2006.01); A61K 33/243 (2019.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 519/00 (2013.01); A61K 33/243 (2019.01); A61K 45/06 (2013.01);
Abstract
The present disclosure relates to novel triazolo-pyrimidine compounds targeting adenosine receptors (especially A1 and A2, particularly A2a). The present disclosure also relates to pharmaceutical compositions comprising one or more of the compounds as an active ingredient, and use of the compounds in the treatment of adenosine receptor (AR) associated diseases, for example cancer such as NSCLC, RCC, prostate cancer, and breast cancer.