The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2023

Filed:

Oct. 24, 2017
Applicants:

Relay Therapeutics, Inc., Cambridge, MA (US);

D. E. Shaw Research, Llc, New York, NY (US);

Inventors:

Fabrizio Giordanetto, New York, NY (US);

Jack Benjamin Greisman, New York, NY (US);

Paul Maragakis, New York, NY (US);

Alexander M. Taylor, Cambridge, MA (US);

Lucian V. Dipietro, Gloucester, MA (US);

Elizabeth H. Kelley, Cambridge, MA (US);

André Lescarbeau, Somerville, MA (US);

Mark Andrew Murcko, Holliston, MA (US);

Levi Charles Thomas Pierce, Somerville, MA (US);

Kelley C. Shortsleeves, Maynard, MA (US);

W. Patrick Walters, Westborough, MA (US);

Sathesh Bhat, Jersey City, NJ (US);

Eric Therrien, Bronx, NY (US);

Markus Kristofer Dahlgren, Shelton, CT (US);

Assignees:

D. E. Shaw Research, LLC, New York, NY (US);

Relay Therapeutics, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of SHP2 phosphatase with the compounds and compositions of the invention. The present invention further relates to, but is not limited to, methods for treating disorders associated with SHP2 deregulation with the compounds ad compositions of the invention.


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