The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2023

Filed:

Mar. 15, 2019
Applicant:

Nanjing Chuangte Pharmaceutical Technology Co., Ltd., Jiangsu, CN;

Inventors:

Yongqiang Zhu, Jiangsu, CN;

Yang Yang, Jiangsu, CN;

Ou Hai, Jiangsu, CN;

Zhaogang Liu, Jiangsu, CN;

Chao Feng, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/06 (2006.01); C07C 309/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/06 (2013.01); C07C 309/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

Disclosed in the present invention are a crystal form of monomethanesulfonate of a deuterated 3-(4,5-substituted aminopyrimidine)phenyl compound as represented by formula I, and a preparation method therefor. The crystal form is highly stable, can be used for treatment or prevention of diseases or conditions by means of epidermal growth factor receptors (EGFRs) in some mutation forms, can effectively inhibit the growth of a variety of tumor cells, and have an inhibiting effect on other proteases of EGFR and Her families, and thus can be used for preparing antitumor drugs.


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