The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2023

Filed:

Nov. 06, 2018
Applicant:

Jubilant Prodel Llc, Yardley, PA (US);

Inventors:

Chandregowda Venkateshappa, Bangalore, IN;

Athisayamani Jeyaraj Duraiswamy, Bangalore, IN;

Rama Kishore V P Putta, Bangalore, IN;

Sridharan Rajagopal, Bangalore, IN;

Assignee:

JUBILANT PRODELL LLC, Yardley, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01); A61P 35/04 (2006.01); A61K 45/06 (2006.01); C07D 239/52 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); A61K 45/06 (2013.01); A61P 35/04 (2018.01); C07D 239/52 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01);
Abstract

The compounds of Formula Ib, Formula Ia, and Formula I are described herein along with their polymorphs, stereoisomers, tautomers, prodrugs, solvates, and pharmaceutically acceptable salts thereof. The process of preparation of the compounds of Formula Ib, Formula Ia, and Formula I is also described. The compounds described herein, their polymorphs, stereoisomers, tautomers, prodrugs, solvates, and pharmaceutically acceptable salts thereof are 2-(benzyloxy)pyrimidine derivatives that are inhibitors of PD-1/PD-L1 activation.


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