The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2023
Filed:
Mar. 30, 2018
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
Jeffrey T. Borenstein, Newton, MA (US);
Alla A. Gimbel, Medford, MA (US);
Jose A. Santos, Westwood, MA (US);
Daniel T. Doty, Arlington, MA (US);
Nathan F. Moore, Providence, RI (US);
Louis B. Kratchman, Quincy, MA (US);
James Truslow, Boston, MA (US);
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
Abstract
Systems and methods for conducting assays on tissue fragment samples including providing a suspension maintaining pump, and a plurality of fluid reservoirs, wherein the fluid reservoirs are configured to hold a volume of fluid. The fluid reservoirs are fluidically coupled to a microfluidic assay chip, wherein the microfluidic assay chip includes a plurality of parallel assay channels, a first inlet port for introduction of a tissue fragment sample into the microfluidic assay ship, and a second inlet port coupled to the fluid reservoir. Each channel of the microfluidic assay chip also includes a retention barrier configured to trap the tissue fragment sample such that the fluid perfuses through the tissue sample, as well as an outlet port fluidically coupled to a waste receptacle.