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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11628208 B1

PDFFull Text
Date of Patent:
Apr. 18, 2023

Filed:

Nov. 30, 2020

System and method for microneedle delivery of microencapsulated vaccine and bioactive proteins

Applicant:

The Corporation of Mercer University, Macon, GA (US);

Inventor:

Martin J. D'Souza, Duluth, GA (US);

Assignee:

THE CORPORATION OF MERCER UNIVERSITY, Macon, GA (US);

Attorneys:

Barnes & Thornburg LLP

Jason A. Bernstein

Primary Examiner:

Anand U Desai

Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12N 7/00 (2006.01); A61K 39/165 (2006.01); A61K 39/095 (2006.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01); A61K 31/245 (2006.01); A61K 31/46 (2006.01); A61K 31/5383 (2006.01); A61K 31/7036 (2006.01); A61K 31/7048 (2006.01); A61K 31/7088 (2006.01); A61K 31/727 (2006.01); C12N 15/88 (2006.01); A61K 9/16 (2006.01); C12N 5/071 (2010.01); A61K 39/155 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/00 (2013.01); A61K 9/0021 (2013.01); A61K 9/1652 (2013.01); A61K 9/5161 (2013.01); A61K 9/5169 (2013.01); A61K 9/5192 (2013.01); A61K 31/245 (2013.01); A61K 31/46 (2013.01); A61K 31/5383 (2013.01); A61K 31/7036 (2013.01); A61K 31/7048 (2013.01); A61K 31/7088 (2013.01); A61K 31/727 (2013.01); A61K 39/0008 (2013.01); A61K 39/0011 (2013.01); A61K 39/095 (2013.01); A61K 39/155 (2013.01); A61K 39/165 (2013.01); C12N 5/0677 (2013.01); C12N 7/00 (2013.01); C12N 15/88 (2013.01); A61K 48/00 (2013.01); A61K 2039/52 (2013.01); A61K 2039/54 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55594 (2013.01); A61K 2039/57 (2013.01); C12N 2533/72 (2013.01); C12N 2533/74 (2013.01); C12N 2760/18434 (2013.01); C12N 2760/18534 (2013.01);
Abstract

A method for producing at least one microneedle containing a vaccine for transdermal delivery of the vaccine to a patient includes preparing microparticles or nanoparticles of encapsulated vaccine by preparing a solution comprising a vaccine antigen and a biocompatible polymer matrix; and spray drying the solution to form the microparticles or nanoparticles. The method includes the further steps of preparing a film composition including at least one pre-polymer solution; preparing a suspension comprising the microparticles or nanoparticles and the film composition; loading the suspension into a 3D printer; printing, via the 3D printer, at least one microneedle made from the suspension; and, converting the pre-polymer solution into a cross-linked biopolymer by exposing the at least one microneedle to UV light. Also disclosed are microneedles containing a vaccine for transdermal delivery.

Find Patent Forward Citations

D'Souza, Martin. (2023). System and method for microneedle delivery of microencapsulated vaccine and bioactive proteins (U.S. Patent No. 11628208). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11628208

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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