The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2023

Filed:

May. 03, 2021
Applicant:

Bioved Pharmaceuticals, Inc., San Jose, CA (US);

Inventors:

Deepa Chitre, Los Gatos, CA (US);

Debendranath Dey, Fremont, CA (US);

Satej R Nadkarni, San Jose, CA (US);

Assignee:

Bioved Pharmaceuticals, Inc, San Jose, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/9066 (2006.01); A61K 36/324 (2006.01); A61K 31/25 (2006.01); A61K 45/06 (2006.01); A61K 36/268 (2006.01); A61K 31/375 (2006.01); A61K 31/315 (2006.01); A61K 31/197 (2006.01);
U.S. Cl.
CPC ...
A61K 36/9066 (2013.01); A61K 31/197 (2013.01); A61K 31/25 (2013.01); A61K 31/315 (2013.01); A61K 31/375 (2013.01); A61K 36/268 (2013.01); A61K 36/324 (2013.01); A61K 45/06 (2013.01);
Abstract

Methods and compounds for preventing and arresting COVID-19 morbidity and mortality, via inhibition of Interleukin-6, TNF-alpha, and other cytokines, and via reduction of C-reactive proteins are provided. Analyses of patients with COVID-19 complicated by ARDS, for example, show highly activated cytotoxic T-cells, resulting from hyperactivation of the immune system. A significant surge of Interleukin-6 (IL-6), TNF-α, and other cytokines are thought to be mediators of this enhanced T-cell activity, and runaway inflammation that are dangerous or fatal to the patient. Example oral formulations dubbed BV-4051 and Artovid-20 provide prophylaxis and treatment of these conditions caused by COVID-19 disease. The example formulations contain plant extracts boosting the human immune system and targeting the detrimental effects of the SARS-CoV-2 virus in its various strains.


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